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  • WCLC 2016: Interview with Prof. Solange Peters

    Editor in Chief

    The Resource Centre “Milestones in non-small-cell lung cancer” owes its title to the tremendous progress that has been made in the treatment of advanced non-small-cell lung cancer with targeted therapy and immunotherapy. Remaining knowledge gaps include the approach to take in patients insensitive to immunotherapy as well as the lack of standardization with regard to trial strategy and design. This interview with Prof. Solange Peters, Medical Oncology Service Chief, Oncology Department, University Hospital of Lausanne, Switzerland, reviews these topics.
  • WCLC 2016: Dr. Stefan Zimmermann on highlights from the World Conference on Lung Cancer

    Managing Editor

    The regulation of tobacco control, immunotherapy, and targeted therapy in ALK- and KRAS-rearranged lung cancer were some of the highlights at the World Conference on Lung Cancer 2016 in Vienna, says Dr. Zimmermann, Senior Resident in Medical Oncology at Fribourg Hospital, Switzerland. He and the other editors of the Resource Centre “Milestones in non-small-cell lung cancer” invite you to visit this platform to keep abreast of recent scientific developments in this area.
  • ECCO 2017 webcasts - Part 1

    Welcome & Introduction" by Nicholas Thatcher

    Nicholas Thatcher introduces the symposium topic: “Debating the optimal management in advanced and metastatic lung cancer: The right treatment for the right patient at the right time”.
    Nicholas Thatcher - Welcome and Introduction at ECCO 2017 NSCLC
  • ECCO 2017 webcasts - Part 2

    'Identifying the right patient: histological and molecular profiling challenges' by Keith Kerr

    With more insights into the molecular characteristics of lung cancer cells and the evolvement of new technologies diagnosis and treatment is more targeted and equally complicated – a lecture of Keith Kerr, University of Aberdeen.
    Keith Kerr -  Identifying the right patient: histological and molecular profiling challenges at ECCO 2017 NSCLC
  • ECCO 2017 webcasts - Part 3

    "Maximizing Treatment Outcomes in Patients with Advanced Metastatic Lung Cancer" by Giorgio V Scagliotti

    Giorgio Scagliotti builds a modern-day algorithm for selecting individualized therapies in nonsquamous non-small cell lung cancer and squamous non-small cell lung cancer based on molecular biomarkers and clinical trial results. He highlights the improvements in our abilities to better target therapies but also addresses the limitations in translating clinical trial data to the clinical setting, and discusses the gaps in therapy that still remain in this patient population. Finally, he comments on the issues remaining with effectively incorporating immunotherapy strategies into the clinic.
    Giorgio V Scagliotti - Maximizing Treatment Outcomes in Patients with Advanced Metastatic Lung Cancer at ECCO 2017 NSCLC
  • ECCO 2017 webcasts - Part 4

    "The right time, the right sequence" by Nicholas Thatcher

    Using a case study in a 76-year old male with squamous non-small cell lung cancer, Dr Thatcher explores the significance of clinical trial results from a clinician’s perspective versus those of a patient. He suggests that while a 6-week increase in overall survival may be considered to be a minimal improvement by clinicians, to the patient it could mean a great deal. He also challenges the guidelines that currently define the age that is “too old” for chemotherapy, citing evidence that in people over 70 years of age chemotherapy can have substantial benefits.
    Nicholas Thatcher - The Right Time, the Right Sequence and the Right Combination for the Right Result at ECCO 2017 NSCLC
  • ECCO 2017 webcasts - Part 5

    "Medical management of advanced NSCLC" by Christian Manegold

    Three antiangiogenic agents have been incorporated into current treatment algorithms for non-small cell lung cancer (NSCLC). Dr Manegold reviews clinical trial data that supports the addition of these agents to platinum-based chemotherapy, as well as the addition to other targeted agents such as monoclonal antibodies or small tyrosine kinase inhibitors. He discusses early results from small clinical trials that combine antiangiogenic agents with immune-checkpoint inhibitors. He also explores the questions that remain for creating a treatment algorithm for combining antiangiogenic agents with immune-checkpoint inhibitors for NSCLC therapy.
    Christian Manegold - Medical management of advanced NSCLC at ECCO 2017
  • WCLC 2016: Interview with Prof. Nir Peled

    Advisory Editor

    Biomarker testing has opened the door for precision medicine based on an individual patient’s tumor characteristics rather than histology alone. Key biomarkers in patients with advanced non-small-cell lung cancer are epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) gene rearrangements, KRAS mutations or programmed death-ligand 1 (PD-L1) expression. Limitations to this approach, e.g. the sensitivity of the diagnostic tools or tissue availability, should be overcome by modern molecular technologies.
  • WCLC 2016: Interview with Prof. Tom Stinchcombe

    Advisory Editor

    Immunotherapy with nivolumab and pembrolizumab or a combination therapy have shown improvements in the survival of patients with squamous non-small-cell lung cancer. With many immunotherapeutic agents in the developmental phase, assigning patients to the best therapy will become ever more important and challenging.
  • WCLC 2016: Interview with Prof. Enriqueta Felip

    This session focuses on the overall landscape of ALK inhibitors for treatment of NSCLC. Enriqueta Felip, Head of the Medical Oncology Service of the Thoracic Tumors Committee, Vall d’Hebron University Hospital, Barcelona, Spain, discusses the various ALK inhibitors currently available, including crizotinib, ceritinib and alectinib, as well as the possible treatment modalities with these drugs either as monotherapy or in combination. She also provides a brief overview of the various randomized trials which have shown positive results with these inhibitors and stresses the need for further trials in order to obtain more data in this area.


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Please note that Lilly Oncology has no editorial control over the content of this Resource Centre. The Resource Centre and all content therein has been subjected to an independent editorial review.

Perspectives in Lung Cancer 2017

How I optimize treatment for my NSCLC patients with advanced and aggressive disease

Now available: Webcast on demand


ECCO 2017

Debating the optimal management in advanced and metastatic lung cancer: The right treatment for the right patient at the right time

Did you miss the Satellite Symposium?

Now available: Webcast on demand

This educational activity is provided by Elsevier. Independent sponsorship for this educational activity was provided by Lilly Oncology.

Interactive Case Reports

Read more about recent cases from the Journal of Thoracic Oncology. Test your knowledge and answer the questions following the case to get immediate feedback.